ACE

The angiotensin converting enzyme (ACE) is an enzyme that converts angiotensin I to angiotensin II. Angiotensin-converting enzyme (ACE), a key enzyme in RAS, and its connection to cardiovascular risk factors and CVDs.

The renin-angiotensin-aldosterone system (RAAS) is one of the most important systems regulating blood pressure and cardiovascular homeostasis and appears to have an important role for development of CVDs. Angiotensin converting enzyme (ACE) is integral to the renin-angiotensin system (RAS), which maintains blood pressure by regulation of well as fluid, salt balance and vascular tension.

It is test primarily used in diagnosis of Sarcoidosis, an increased level of ACE is found in the blood, it also helps determine the levels of ACE Enzyme in the blood.

Sarcoidosis is a disease characterized by the growth of tiny collections of inflammatory cells (granulomas) in any part of your body — most commonly the lungs and lymph nodes. But it can also affect the eyes, skin, heart and other organs. Granulomas affect the structure and function of tissues. Cells outside of granulomas produce excess ACE which is finally detected in a test.

Significant increase in levels of serum Angiotensin converting enzyme (ACE), are observed in most patients with active pulmonary sarcoidosis. An increased level of ACE with clinical symptoms of Sarcoidosis confirms a diagnosis.

 

Features and Benefits of ACE:

• Liquid-stable, ready–to-use reagents
• Single Reagent
• Small pack size
• Excellent accuracy and precision
• Dedicated calibrator for optimal performance
• Measuring range is 3-150 U/L